Affiliations, Disposition of the patients. Related content doi: 10.1002/14651858.CD010952.pub2. Arthritis Rheumatol 2018;70(Suppl 10). Serious AEs were similar across treatment arms. 2019;71(suppl 10), Abstract 1817; and Foley C et al. Details are given according to the Consolidated Standards of Reporting Trials (, Major secondary outcomes investigating disease activity, function, and quality of life among patients treated with placebo (, Spondyloarthritis Research Consortium of Canada (. Arthritis Rheumatol. Arthritis Rheumatol. Arthritis Rheumatol. 2016 Oct;68 Suppl 10:1-4550. doi: 10.1002/art.39977. Ann Rheum Dis. van der Heijde D, Cheng-Chung Wei J, Dougados M, Mease P, Deodhar A, Maksymowych WP, Van den Bosch F, Sieper J, Tomita T, Landewé R, Zhao F, Krishnan E, Adams DH, Pangallo B, Carlier H; COAST-V study group. Conclusion: Therapeutic approaches for psoriatic arthritis (PsA) include non-pharmacologic therapies, symptomatic treatments, tumor necrosis factor inhibitors, interleukin inhibitors, cytotoxic T lymphocyte antigen 4 … Arthritis Rheumatol. 2020 Dec;7(4):759-774. doi: 10.1007/s40744-020-00225-4. Cedola F, Coras R, Fernandez-Bustamante M, et al. Plain Text. Arthritis Rheumatol. Arthritis Rheumatol. Growth and development of patients with polyarticular-course juvenile idiopathic arthritis … Effectiveness of switching between TNF inhibitors in patients with axial spondyloarthritis: is the reason to switch relevant? Upadacitinib rotated-square. Conversion rates of abstracts presented at the Urological Society of Australia and New Zealand (USANZ) Annual Scientific Meeting into full-text journal articles. 2017 ACR/ARHP Annual Meeting Abstract Supplement.  |  JAK inhibitors rotated-square. Arthritis Rheumatol . Arthritis Rheumatol. Therapeutic Advances in Musculoskeletal Disease 2019 10.1177/1759720X19864492 Download Citation If you have the appropriate software installed, you can download article citation data to the citation manager of your choice. In December 2018, Idorsia initiated a multiple-dose, efficacy and safety study with cenerimod for the treatment of adult patients with moderately to severely active, … Arthritis Rheumatol. 114), 16–23. Arthritis Rheumatol. As a key manifestation, it has been included in the Classification Criteria for Psoriatic Arthritis (CASPAR) and as a treatment domain for the Group for Research and Assessment of Psoriasis and Psoriatic Arthritis (GRAPPA) treatment guidelines . HHS Guselkumab rotated-square. 3 Data on File, Mallinckrodt, 2019. HHS 2019;71(suppl 10), Abstract 2722; Foley C et al. 2019;71(suppl 10).  |  2019 Update of the American College of Rheumatology/Spondylitis Association of America/Spondyloarthritis Research and Treatment Network Recommendations for the Treatment of Ankylosing Spondylitis and Nonradiographic Axial Spondyloarthritis. 10. 10). Arthritis Rheumatol 2018;70(Suppl 10). Deodhar A, van der Heijde D, Gensler LS, Kim TH, Maksymowych WP, Østergaard M, Poddubnyy D, Marzo-Ortega H, Bessette L, Tomita T, Leung A, Hojnik M, Gallo G, Li X, Adams D, Carlier H, Sieper J; COAST-X Study Group. 2019;71(10):1599-1613. Overall TEAEs for UPA and Active Comparators (E/100 PYs [95% CI]) ! Arthritis Rheumatol. View this table: Table. Disposition of the patients. © 2019, American College of Rheumatology. Arthritis Rheumatol. In this phase III randomized, double-blind, placebo-controlled trial, adult patients with an inadequate response to or intolerance of 1 or 2 TNFi and an established diagnosis of axial SpA (according to the Assessment of SpondyloArthritis international Society [ASAS] criteria for radiographic axial SpA, with radiographic sacroiliitis defined according to the modified New York criteria and ≥1 feature of SpA) were recruited and randomized 1:1:1 to receive placebo or 80-mg subcutaneous ixekizumab every 2 weeks (IXEQ2W) or 4 weeks (IXEQ4W), with an 80-mg or 160-mg starting dose. ACR/ARP 2019 rotated-square. We evaluated GUS efficacy and safety in a Phase 3, double-blind, PBO-controlled trial in … Epub 2019 Aug 21. Anti-carbamylated proteins antibody repertoire in rheumatoid arthritis: evidence of a … Arthritis Rheumatol. For a searchable version of these abstracts, please visit www.acrabstracts.org. Arthritis Rheumatol 2019;71 (Suppl. Abstract 1482. Impact of Ixekizumab on Work Productivity in Patients with Ankylosing Spondylitis: Results from the COAST-V and COAST-W Trials at 52 Weeks. Missing Disclaimer Information in the Title‐Page Footnotes of the Article by Rims et al (Arthritis Rheumatol, April 2019) Pages: 907 First Published: 27 May 2019 Baker NA, Barbour KE, Helmick CG, Zack MM, Al snih S. Arthritis and cognitive impairment in older adults. Arthritis Rheumatol 2019; 71 (suppl 10) ACR/ARP 2019; Atlanta, Georgia, USA: 8–13 November. For a searchable version of these abstracts, please visit www.acrabstracts.org. Related topics. Arthritis & Rheumatology published by Wiley Periodicals, Inc. on behalf of American College of Rheumatology. -, Braun J, Sieper J. Ankylosing spondylitis. 2019;71(suppl 10). 6:214. doi: 10.3389/fmed.2019.00214. 2019;71(suppl 10… 2019;71(suppl 10… 2019; 71 (suppl 10). UCB. 2020 Oct 1;59(Supplement_4):iv79-iv89. ACR/ARP 2019 rotated-square. Ward MM, Deodhar A, Gensler LS, Dubreuil M, Yu D, Khan MA, Haroon N, Borenstein D, Wang R, Biehl A, Fang MA, Louie G, Majithia V, Ng B, Bigham R, Pianin M, Shah AA, Sullivan N, Turgunbaev M, Oristaglio J, Turner A, Maksymowych WP, Caplan L. Arthritis Care Res (Hoboken). Arthritis Rheumatol. Arthritis Rheumatol. Lancet 2017;390:73–84. ACR/ARP 2019 … Flare reduction and oral corticosteroid taper in patients with active SLE treated with anifrolumab in 2 phase 3 trials. In a rheumatic disease population (51.4% RA, 23.8% axial SpA, and 19.6% PsA), patients reported that their disease had moderate to severe effects on their quality of life (51.9%), work/daily activities (49.2%), emotional well-being (41.0%), personal relationships (26.0%), and close relatives’ lives (32.3%). Response to baricitinib at 4 weeks predicts response at 12 and 24 weeks in patients with rheumatoid arthritis: results from two phase 3 studies. Arthritis Rheumatol. Marzo-Ortega H, Mease PJ, Rahman P, Navarro-Compán V, Strand V, Dougados M, Combe B, Wei JC, Baraliakos X, Hunter T, Sandoval D, Li X, Zhu B, Bessette L, Deodhar A. Rheumatol Ther. Please enable it to take advantage of the complete set of features! A randomized, double-blind, placebo-controlled, sixteen-week study of subcutaneous golimumab in patients with active nonradiographic axial spondyloarthritis. Details are given according to the Consolidated Standards of…, Proportion of patients achieving A , 40% improvement in disease activity according to…, Major secondary outcomes investigating disease…, Major secondary outcomes investigating disease activity, function, and quality of life among patients…, Spondyloarthritis Research Consortium of Canada…, Spondyloarthritis Research Consortium of Canada ( SPARCC ) magnetic resonance imaging ( MRI…, NLM DMARDs rotated-square. 2019, 71, 1232–1240. 2018;70(suppl 10). 2019;71(suppl 10):abstract 2707. Background/Purpose: Olokizumab (OKZ) is a new humanized monoclonal antibody targeting IL-6 1, 2. 2015 Oct;67(10):2702-12. doi: 10.1002/art.39257. Allanore Y, Denton C, Khanna D, Soubrane C, Esperet C, Marrache F, et al. 2020 Dec;7(4):667-684. doi: 10.1007/s40744-020-00234-3. [PMC free article] [Google Scholar] Arthritis Rheumatol. Safety profile of baricitinib for the treatment of rheumatoid arthritis up to 7 years: an updated integrated safety analysis. Presented at: 2019 ACR/ARP Annual Meeting; November 8-13, 2019… NIH Sieper J, van der Heijde D, Dougados M, Maksymowych WP, Scott BB, Boice JA, Berd Y, Bergman G, Curtis S, Tzontcheva A, Huyck S, Weng HH. Lancet. UL1 TR000371/TR/NCATS NIH HHS/United States, Reveille JD, Witter JP, Weisman MH. Furst D, Wan G, Liu J, Zhu J, Bartels-Peculis L, Panaccio M, Fleischmann R. Improved Patient-Reported Outcomes in Patients with Persistently Active Rheumatoid Arthritis Following Treatment with Repository Corticotropin Injection [abstract]. Abstract 1482. J Rheumatol 1996;23:1866-71. Epub 2020 Aug 19. 2014;371:326–38. 2020 Aug 28;11:1986. doi: 10.3389/fimmu.2020.01986. [5]van Vollenhoven, et al . Arthritis Rheumatol. Presented at: 2019 ACR/ARP Annual Meeting; November 8-13, 2019; Atlanta, GA. Epub 2019 Mar 8. Epub 2019 Aug 28. UCB. Arthritis Rheumatol. 2016 Feb;68(2):282-98. doi: 10.1002/art.39298.  |  Robinson PC, Sengupta R, Siebert S. Non-radiographic axial spondyloarthritis (nr-axSpA): advances in classification, imaging and therapy. Likewise, patients with PsA have been reported to have an increased risk of comorbidities and adverse events (AEs), including serious infections (SIs), compared with patients with psoriasis [ 13 , 14 ]. Arthritis Rheumatol. Inflammatory bowel disease and anterior uveitis in patients treated with ixekizumab for radiographic axial spondyloarthritis: results from two phase 3 studies through 52 weeks. Secondary outcomes and safety were also assessed. Clipboard, Search History, and several other advanced features are temporarily unavailable. Ixekizumab for patients with non-radiographic axial spondyloarthritis (COAST-X): a randomised, placebo-controlled trial. Clin Rheumatol 2017;36:2667-71. [5]van Vollenhoven, et al . Arthritis Rheumatol. Arthritis Rheumatol. [4]Sieper J, … Epub 2015 Mar 20. National Center for Biotechnology Information, Unable to load your collection due to an error, Unable to load your delegates due to an error, Collaborators, View this table: Table. Related content 01-11-2019 | Psoriatic arthritis | ACR/ARP 2019 … To investigate the efficacy and safety of ixekizumab in patients with active radiographic axial spondyloarthritis (SpA) and prior inadequate response to or intolerance of 1 or 2 tumor necrosis factor inhibitors (TNFi). 2019;71(suppl 10). Arthritis Rheumatol 2019; 71 Arthritis Rheumatol 2019; 71 (suppl 10) ACR/ARP 2019; Atlanta, Georgia, USA: 8–13 November. Cimzia ® (certolizumab pegol) approved by FDA for treatment of adults with active ankylosing spondylitis [press release]. 2019; 71 (suppl 10). If you do not receive an email within 10 minutes, your email address may not be registered, and you may need to create a new Wiley Online Library account. [Google Scholar] ... with computed tomography-based tool for the evaluation of joint counts and disease activity in patients with rheumatoid arthritis.  |  ACR/ARP 2019 rotated-square. Authors Atul Deodhar 1 , Denis Poddubnyy 2 , Cesar Pacheco-Tena 3 , Carlo Salvarani 4 , Eric Lespessailles 5 , … 2016; 68 (suppl 10) Smolen JS, Schöls M, Braun J, et al. Myocardial inflammation, measured using 18-fluorodeoxyglucose positron emission tomography with computed tomography, is associated with disease activity in rheumatoid arthritis. 2019; 71 (4):496–506. Entheses are tendons or ligaments that attach to the bone. Patient-reported outcomes (PROs) aid in rheumatoid arthritis (RA) management, but it is not well understood which measures would be most relevant to the rheumatologists for making treatment decisions. Rheumatol. COVID-19 is an emerging, rapidly evolving situation. 2019;71(suppl 10), Abstract 1817; and Foley C et al. Epub 2012 Feb 2. 1 There is also insufficient guidance on BMD testing in patients with PsA as per recent major clinical practice guidelines. -, Ward MM, Deodhar A, Akl EA, Lui A, Ermann J, Gensler LS, et al. Previous Issue | Next Issue. Among RA pts, the … See this image and copyright information in PMC. van der Heijde D., Arthritis Rheumatol 2019; 71(Suppl 10), abs 0937 Ankylosing Spondylitis A Multicenter, Open-Label Extension Study to Evaluate the Long Term Safety and Efficacy of … Related content 2015 Oct;67 Suppl 10:1-4046. doi: 10.1002/art.39448. Castellanos-Moreira R et al. 2015 ACR/ARHP Annual Meeting Abstract Supplement. 2019;71(7):1101-11. Behcet’s syndrome (BS) is a variable vessel vasculitis that often follows a relapsing and remitting course. Benedetti D, et al. Cardiovascular disease rotated-square. Background/Purpose: Non-radiographic axial spondyloarthritis (nr-axSpA) and ankylosing spondylitis (AS) are considered part of the spectrum of axSpA. This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features! If you do not receive an email within 10 … The safety profile of secukinumab through Wk 52 was consistent with previous reports.3-4 References: [1]McInnes IB, et al. Ann Rheum Dis 2017;76:978–91. National Center for Biotechnology Information, Unable to load your collection due to an error, Unable to load your delegates due to an error. Background/Purpose: Guselkumab (GUS), an anti-interleukin-23p19 monoclonal antibody, is approved to treat PsO. [4]Fleischmann, et al . Front. Risk of venous thromboembolism in rheumatoid arthritis patients initiating biologic and non-biologic DMARDs, a population-based study. At week 16, significantly higher proportions of IXEQ2W patients (n = 30 [30.6%]; P = 0.003) or IXEQ4W patients (n = 29 [25.4%]; P = 0.017) had achieved an ASAS40 response versus the placebo group (n = 13 [12.5%]), with statistically significant differences reported as early as week 1 with ixekizumab treatment. 2018 Dec 8;392(10163):2441-2451. doi: 10.1016/S0140-6736(18)31946-9. [2]Baraliakos X, et al. 2019 Oct;71(10):1285-1299. doi: 10.1002/acr.24025. Arthritis Rheumatol. Kroon FP, van der Burg LR, Ramiro S, Landewé RB, Buchbinder R, Falzon L, van der Heijde D. Cochrane Database Syst Rev. Pages: 1-5420. Epub 2015 Sep 24. Arthritis Rheumatol. The modified Rodnan skin score (mRSS) is a widely used tool for the assessment of the extent and degree of skin … © 2018 The Authors. The purpose of … Inflammatory bowel disease and anterior uveitis in patients treated with ixekizumab for radiographic axial spondyloarthritis: results from two phase 3 studies through 52 weeks. Arthritis Rheumatol. 2015 Jul;14(7):622-32. doi: 10.1016/j.autrev.2015.03.003. Li LY, Lu N, Lacaille D, Xie H, Esdaile J, Avina-Zubieta JA. Med. Research on the effect of psoriatic arthritis (PsA) on bone mineral density (BMD) is inconsistent. -, Sieper J, Poddubnyy D. Axial spondyloarthritis. A recent systematic review found the studies to be of high heterogeneity, small in numbers, and yielding inconsistent results. COVID-19 is an emerging, rapidly evolving situation. Arthritis Rheumatol. Arthritis Rheumatol. Related topics. 2019:1-13. 2019;71(10):1599-1613. Lancet. Mallinckrodt ARD LLC. 2019;71(suppl 10), Abstract 2722; Foley C et al. Schwartzman S, Deodhar A, Kronbergs A, et al. Manica SR, Sepriano A, Pimentel-Santos F, Gouveia N, Barcelos A, Branco JC, Bernardes M, Ferreira RM, Vieira-Sousa E, Barreira S, Vinagre F, Roque R, Santos H, Madeira N, Rovisco J, Daniel A, Ramiro S. Arthritis Res Ther. Request Username Can't sign in? 2017 Oct;69 Suppl 10:1-4426. doi: 10.1002/art.40321. -. Alfaleh MA, Alsaab HO, Mahmoud AB, Alkayyal AA, Jones ML, Mahler SM, Hashem AM. 2015;67(Suppl 10):abstract 1050. Results: BJU Int. Morand E, et al. 2019;71(Suppl 10):1894. Non-steroidal anti-inflammatory drugs (NSAIDs) for axial spondyloarthritis (ankylosing spondylitis and non-radiographic axial spondyloarthritis). Genovese M, Smolen J, Takeuchi T, et al. 2019;71(Suppl 10… Here we present the results of the first phase III study of OKZ in patients with Rheumatoid Arthritis … Get the latest public health information from CDC: https://www.coronavirus.gov, Get the latest research information from NIH: https://www.nih.gov/coronavirus, Find NCBI SARS-CoV-2 literature, sequence, and clinical content: https://www.ncbi.nlm.nih.gov/sars-cov-2/. Trial registration: 2015;386(9999):1137–46. Volume 71, Issue S10. 10.1136/lupus-2019-lsm.199 Background Baricitinib (Bari), an oral selective inhibitor of Janus kinase (JAK)1 and JAK2, has been approved for the treatment of rheumatoid arthritis (RA) in over 50 countries including the United States, European countries, and Japan. : 10.1016/S0140-6736 ( 18 ) 31946-9 AM, Saalfeld W. 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